Skip to content
Site Tools
Increase font size Decrease font size Default font size

Matgas Publications

Matgas Publications
  • article
  • Daintree, L. S. and Kordikowski, A. and York, P.
  • Separation processes for organic molecules using SCF technologies
  • Advanced Drug Delivery Reviews
  • 2008
  • 60
  • 351--372
  • 3
  • Supercritical fluids have been applied for many years for the separation of solutes from solids or solute mixtures in both exploratory and industrial applications. In the pharmaceutical industry the generation of pure solid states without impurities is important as the presence of impurities can result in a change in chemical properties or lead to physical instability. The literature on the separation and purification of solutes from solid matrices and solute mixtures using supercritical fluids, with the main emphasis on pharmaceutically important molecules, is reviewed in this article. Also discussed is the application of supercritical fluids in the control of process impurities such as chemical intermediates and residual solvent and in polymorphic control and chiral resolution. As the generation of organic molecules of pharmaceutical interest with high purity is important in pharmaceuticals this review additionally provides a brief overview of highly selective chemical reactions in supercritical fluids. (c) 2007 Elsevier B.V. All rights reserved.

SYMPOSIUM

saftlogotransp
20 YEARS OF THE SAFT EQUATION
Recent advances and challenges
Barcelona
September 19-21, 2010

Director's Message

welcome2

Annual Reports

 

Year 2009

MATGAS 2000 A.I.E.

MATGAS 2000 A.I.E. is non-profit making economic interest group dedicated to meeting R+D demands in the field of materials and gases from a broad perspective.

Contact

SOST-CO2

 

 
CENIT - Ingenio 2010